Biomarkers in drug hypersensitivity

Biomarkers in drug hypersensitivity

drug hypersensitivity

Drug-induced hypersensitivity reactions play a prominent role among adverse drug effects, and constitute a major health problem. It has been suggested that up to 6% of all hospital admissions are related to these reactions. Biomarkers, especially those based on pharmacogenomics testing, have proved to be extremely useful for type A adverse drug reactions. Clinical practice guidelines based on biomarker testing are presently being developed and updated for type A adverse drug reactions. In contrast, little attention has been paid to the potential use of biomarkers in type B adverse reactions, characterized by the occurrence of reactions not directly related to the pharmacological properties of the drug. Drug-induced hypersensitivity belongs to those type B reactions.

Jose A. G. Agundez , et al

https://www.frontiersin.org/research-topics/4326/biomarkers-in-drug-hypersensitivity

Frontiers Media SA

2017

Baihaqi

Creative Commons

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