Carotid Body: A New Target for Rescuing Neural Control of Cardiorespiratory Balance in Disease

Carotid Body: A New Target for Rescuing Neural Control of Cardiorespiratory Balance in Disease

Carotid Body

The carotid body (CB) is the main arterial chemoreceptor in charge of adjusting ventilatory and cardiovascular function during changes in arterial blood gases. Regardless this essential function, the CB has been implicated in the sensing of other physiological signals such as changes in blood flow and glucose levels. More important, malfunction of the CB chemoreceptors has been associated with the progression and deterioration of several disease states such as hypertension, heart failure, renal failure, insulin resistance, diabetes and sleep apnea. Although the mechanisms involved in the alterations of the CB function in pathophysiology are currently under intense research, the development of therapeutic approaches to restore normal CB chemoreflex function remains unsolved.

Rodrigo Del Rio -, Rodrigo Iturriaga -, Harold D. Schultz

https://www.frontiersin.org/research-topics/2694/carotid-body-a-new-target-for-rescuing-neural-control-of-cardiorespiratory-balance-in-disease

Frontiers Media SA

2016

Baihaqi

Creative Commons

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English

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