Cellular Entry of Binary and Pore-Forming Bacterial Toxins

Cellular Entry of Binary and Pore-Forming Bacterial Toxins

Biology

Bridging cellular membranes is a key step in the pathogenic action of both binary and pore-forming bacterial toxins. The former use their translocation domains, containing various structural motifs, to ensure efficient delivery of the toxic component into the host cell, while the latter act on the cellular membrane itself. In either case, the integrity of the membrane is compromised via targeted protein–lipid and protein–protein interactions triggered by specific signals, such as proteolytic cleavage or endosomal acidification.

Alexey S. Ladokhin (Ed.)

https://www.mdpi.com/books/pdfview/book/531

MDPI - Multidisciplinary Digital Publishing Institute

2018

Baihaqi

Creative Commons

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English

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