Electronic Theses and Dissertation

Infeksi Saluran Kemih (ISK) adalah keadaan di mana mikroorganisme patogen terdapat pada saluran kemih. Penelitian ini bertujuan untuk mengetahui perbandingan karakteristik umum E. coli dan K. pneumoniae sensitif karbapenem dengan resistan karbapenem pada penderita ISK berdasarkan parameter usia, jenis kelamin, dan ruang rawat pasien. Penelitian ini menggunakan metode deskriptif dengan mengumpulkan data hasil kultur spesies E. coli dan K. pneumoniae dari sampel urin penderita ISK. Data retrospektif dari Januari 2022 hingga Februari 2024, dan data prospektif dari Maret hingga Mei 2024. Hasil penelitian diketahui jumlah E. coli dan K. pneumoniae sebanyak 381 isolat, 347 isolat (91%) sensitif karbapenem dan 34 isolat (9%) resistan karbapenem. E. coli sebanyak 272 isolat, 256 isolat (94,1%) sensitif karbapenem dan 16 isolat (5,8%) resistan karbapenem. K. pneumoniae sebanyak 109 isolat, 91 isolat (83,4%) sensitif karbapenem dan 18 isolat (16,5%) resistan karbapenem. E. coli banyak ditemukan pada perempuan dengan jumlah 183 isolat, 172 isolat (93,9%) sensitif karbapenem dan 11 isolat (6%) resistan karbapenem. K. pneumoniae banyak ditemukan pada perempuan dengan jumlah 60 isolat, 51 isolat (85%) sensitif karbapenem dan 9 isolat (15%) resistan karbapenem. E. coli banyak ditemukan pada usia 41-60 tahun dengan jumlah 112 isolat, 100 isolat (89,2%) sensitif karbapenem dan 12 isolat (10,7%) resistan karbapenem. K. pneumoniae banyak ditemukan pada usia >60 tahun dengan jumlah 36 isolat, 30 isolat (83,3%) sensitif karbapenem dan 6 isolat (16,6%) resistan karbapenem. E. coli ditemukan pada ruang medik dengan jumlah 156 isolat, 143 isolat (91,6%) sensitif karbapenem dan 13 isolat (8,3%) resistan karbapenem. K. pneumoniae ditemukan pada ruang medik dengan jumlah 52 isolat, 43 isolat (82,6%) sensitif karbapenem dan 9 (17,3%) resistan karbapenem. Kesimpulan dari penelitian ini, E. coli banyak ditemukan pada pasien perempuan, berusia 41-60 tahun, dan dirawat di ruang medik. K. pneumoniae banyak ditemukan pada pasien perempuan, berusia >60 tahun, dan dirawat di ruang medik.

Urinary tract infection (UTI) is a condition in which pathogenic microorganisms are present in the urinary tract. This study aims to compare the general characteristics of carbapenem-sensitive and carbapenem-resistant E. coli and K. pneumoniae in patients with UTI based on the parameters of age, gender, and patient's hospitalization room. This study used a descriptive method by collecting culture data of E. coli and K. pneumoniae species from urine samples of patients with UTI. Retrospective data from January 2022 to February 2024, and prospective data from March to May 2024. The results showed that there were 381 isolates of E. coli and K. pneumoniae, 347 isolates (91%) were carbapenem sensitive and 34 isolates (9%) were carbapenem resistant. E. coli were 272 isolates, 256 isolates (94.1%) were carbapenem sensitive and 16 isolates (5.8%) were carbapenem resistant. K. pneumoniae was 109 isolates, 91 isolates (83.4%) were carbapenem sensitive and 18 isolates (16.5%) were carbapenem resistant. E. coli was mostly found in women with 183 isolates, 172 isolates (93.9%) were carbapenem sensitive and 11 isolates (6%) were carbapenem resistant. K. pneumoniae was mostly found in women with 60 isolates, 51 isolates (85%) were carbapenem sensitive and 9 isolates (15%) were carbapenem resistant. E. coli was mostly found in 41-60 years old with 112 isolates, 100 isolates (89.2%) were carbapenem sensitive and 12 isolates (10.7%) were carbapenem resistant. K. pneumoniae was mostly found at the age of >60 years with a total of 36 isolates, 30 isolates (83.3%) carbapenem sensitive and 6 isolates (16.6%) carbapenem resistant. E. coli was found in the medical room with a total of 156 isolates, 143 isolates (91.6%) were carbapenem sensitive and 13 isolates (8.3%) were carbapenem resistant. K. pneumoniae was found in the medical room with a total of 52 isolates, 43 isolates (82.6%) were carbapenem sensitive and 9 (17.3%) were carbapenem resistant. In conclusion, E. coli was mostly found in female patients, aged 41-60 years, and admitted to the medical room. K. pneumoniae was mostly found in female patients, aged >60 years, and admitted to the medical room.