Electronic Theses and Dissertation

Pasien kanker kolorektal umumnya menjalani laparotomi sebagai bagian dari penatalaksanaannya. Komplikasi awal laparotomi adalah perdarahan, infeksi luka operasi, dan dehiscence anastomosis. Albumin-limfosit merupakan indikator status gizi dan inflamasi yang digabungkan dalam Indeks Gizi Prognostik (IGNP). Penilaian IGNP terkait derajat luka pasca laparotomi pada kanker kolorektal belum banyak dijelaskan.
Tujuan: untuk mengetahui korelasi IGNP terhadap komplikasi luka laparotomi pada pasien kanker kolorektal di RSUD Dr. Zainoel Abidin Banda Aceh.
Metode: Penelitian cross-sectional akan menilai korelasi IGNP terhadap derajat luka pasca operasi dengan South Hampton Wound Scale. Nilai IGNP ditentukan berdasarkan IGNP dan limfosit. Subjek penelitian adalah pasien kanker kolorektal, berusia 18 tahun dan menjalani laparotomi. Penilaian dilakukan pada hari ke-7 pasca laparotomi. Uji Spearman dilakukan untuk mengetahui korelasinya. Hasil: Sebanyak 30 pasien kanker kolorektal sebagai sampel, dengan rerata usia 49,43 tahun (±11,06), jenis kelamin laki-laki (56,7%), adenokarsinoma berdiferensiasi sedang (46,7%), rerata albumin 3,08 (±0,47) dan limfosit 13,93 (±8,22). Setelah dilakukan evaluasi, didapatkan pasien dengan nilai PNI normal memiliki grade South Hampton 1 (23,3%), sedangkan malnutrisi ringan berada pada grade 1 (6,7%) dan 2 (6,7%), malnutrisi sedang berada pada grade 3 (23,3%) dan grade 4 (16,7%) serta malnutrisi berat berada pada grade 4 (16,7%) dan grade 5 (13,3%).
Kesimpulan: Terdapat korelasi yang sangat kuat antara PNI dengan komplikasi luka pascaoperasi pada kanker kolorektal.
Kata kunci: Indeks Gizi Prognostik, skala luka South Hampton, kanker kolorektal, laparotomi

Colorectal cancer patients generally undergo laparotomy as part of the management. The earliest complications of laparotomy are bleeding, surgical wound infection, and anastomotic dehiscence. Albumin-lymphocytes are indicators of nutritional status and inflammation combined in the Prognostic Nutritional Index (PNI). Evaluation of PNI related to the degree of post-laparotomy wounds in colorectal cancer has not been widely explained Objective: to find out the correlation of PNI for laparotomy wound complications in colorectal cancer patients at Dr. Zainoel Abidin General Hospital Banda Aceh Method: A cross-sectional study will assess the correlation of PNI to the degree of post-operative wounds with the South Hampton Wound Scale. PNI values were determined by albumin and lymphocytes. The subjects were colorectal cancer patients, aged 18 years and underwent laparotomy. The assessment was carried out on the 7th day after laparotomy. The Spearman test was performed to determine the correlation. Results: 30 colorectal cancer patients as samples, with an average age of 49.43 years old (±11.06), male (56.7%), moderately differentiated adenocarcinoma (46.7%), average albumin 3.08 (±0.47) and lymphocytes 13.93 (±8.22). After evaluation, we found that patients with normal PNI values had South Hampton grade 1 (23.3%), while mild malnutrition was in grade 1 (6.7%) and 2 (6.7%), moderate malnutrition was in grade 3 (23.3%) and grade 4 (16.7%) and severe malnutrition were in grade 4 (16.7%) and grade 5 (13.3%). Conclusion: There was a very strong correlation between PNI and postoperative wound complications in colorectal cancer. Keywords: Prognostic Nutritional Index, South Hampton wound scale, colorectal cancer, laparotomy