Electronic Theses and Dissertation

Latar Belakang: Gigi tiruan resin akrilik sering digunakan karena sifatnya yang ringan, fleksibel dan mudah dibentuk. Resin akrilik memiliki sifat transparansi, ketahanan terhadap perubahan warna serta ketahanan mekanik yang baik, namun rentan terhadap pembentukan plak dan mikroorganisme seperti Candida albicans akibat porositasnya. Perawatan gigi tiruan dapat dilakukan secara kimiawi menggunakan bahan alami seperti Clitoria ternatea L. (bunga telang) yang mengandung senyawa antimikroba seperti flavonoid, antosianin, saponin dan terpenoid untuk mengurangi pertumbuhan mikroorganisme dan meningkatkan kebersihan gigi tiruan. Metode: Penelitian eksperimental laboratoris ini menggunakan 24 sampel resin akrilik (10x10x1 mm) yang direndam selama 7 jam dalam empat kelompok perlakuan: larutan ekstrak bunga telang 0,8%, 1%, kontrol positif (Chlorhexidine 0,2%), dan kontrol negatif (aquadest). Pertumbuhan Candida albicans dianalisis menggunakan colony counter pada media Sabouraud Dextrose Agar (SDA). Uji statistik Kruskal-Wallis digunakan dengan tingkat signifikansi p < 0,05. Hasil: Hasil analisis menunjukkan perbedaan signifikan (p = 0,000) dalam penghambatan Candida albicans antar kelompok perlakuan. Ekstrak bunga telang, konsentrasi 1%, efektif menghambat pertumbuhan Candida albicans setelah 24 dan 48 jam perendaman. Kesimpulan: Perendaman Basis Gigi Tiruan Akrilik dengan ekstrak bunga telang 0,8% dan 1% memiliki pengaruh terhadap penghambatan pertumbuhan Candida albicans

Background: Acrylic resin dentures are commonly used due to their light weight, flexibility, and ease of shaping. Acrylic resin has properties such as good transparency, color stability, and sufficient mechanical strength, but it is prone to plaque formation and microorganism growth, including Candida albicans, due to its porosity. Denture cleaning can be done chemically using natural substances like Clitoria ternatea L. (butterfly pea), which contains antimicrobial compounds such as flavonoid, antosianin, saponin, and terpenoid to reduce microorganism growth and improve denture hygiene. Methods: This laboratory experimental study used 24 acrylic resin samples (10x10x1 mm), soaked for 7 hours in four treatment groups: butterfly pea flower Extract solution at 0.8% and 1%, positive control (Chlorhexidine 0.2%), and negative control (aquadest). The growth of Candida albicans was analyzed using a colony counter on Sabouraud Dextrose Agar (SDA) media. Statistical analysis was performed using the Kruskal-Wallis test with a significance level of p < 0.05. Results: The analysis showed significant differences (p = 0.000) in the inhibition of Candida albicans across treatment groups. Butterfly pea flower Extract at 1% concentration effectively inhibited Candida albicans growth after 24 and 48 hours of soaking. Conclusion: The soaking of acrylic dentures with 0.8% and 1% butterfly pea flower Extract has an effect on inhibiting the growth of Candida albicans.